What is CBN?
Cannabinol (CBN) has an unusual origin story: it forms when THC oxidizes and degrades over time. That old, dry cannabis that's lost its punch? It's likely high in CBN. This degradation product is mildly psychoactive—about 10% as potent as THC—but its claim to fame is sedation. While research is limited, CBN has become synonymous with sleep products. The sedative reputation may be partly due to the entourage effect when combined with THC's other breakdown products, but users consistently report that CBN helps with sleep.
How It Works
CBN binds to CB1 receptors with about 10% the affinity of THC, explaining its mild psychoactivity. Its sedative effects may come from this CB1 binding combined with possible interactions with other receptor systems. CBN also shows activity at CB2 receptors and may affect TRPV2 channels.
Medical Uses
Insomnia
Primary use; promotes sleep and extends sleep duration
Pain Relief
May provide analgesic effects
Appetite
Stimulates appetite like THC
Antibacterial
Shows activity against antibiotic-resistant bacteria
Inflammation
Anti-inflammatory properties observed
Dosing Guide
Sleep Support
2.5-5mgMild relaxation for sleep
Moderate
5-10mgStrong sleep support
High
10-20mgPotent sedation
Synergies (Entourage Effect)
Enhanced sedative effects; classic 'couch-lock'
Balanced relaxation without strong psychoactivity
Amplified sedative and sleep-promoting effects
Enhanced calming and sleep effects
Research Highlights
- Limited human studies; most evidence is anecdotal
- Demonstrated antibacterial activity in lab studies
- Animal studies suggest pain-relieving properties
- Often combined with THC/CBD in commercial sleep products
Effects
Potential Side Effects
- •Drowsiness (intended effect)
- •Mild psychoactivity at high doses
- •Grogginess if taken too late
- •Dry mouth
Common In
Best Products For CBN
- Sleep tinctures
- Nighttime edibles
- CBN:THC ratio products
Receptor Binding
Legal Status
Legal gray area (derived from THC degradation)
Related Cannabinoids
Medical Disclaimer
This information is for educational purposes only and is not medical advice. Consult with a healthcare provider before using cannabis products, especially if you have existing health conditions or take medications.